理解什么是常规IVF妊娠率与PGD代孕妊娠率

什么是常规IVF妊娠率

常规IVF妊娠率指的是没有使用代孕妈妈和PGD技术下的成功率。各个年龄段综合成功率通常在40%-60%之间。

什么是100% PGD代孕妊娠率 (也称为SAP PGD妊娠)

100% PGD代孕妊娠率也是98% 24染色体PGD代孕妊娠率。通常情况下,妊娠失败的主要原因之一是移植没有经过PGD筛查的胚胎。玉兰代孕妊娠成功率在98%左右的基本前提是通过RGI的新24 -染色体检测分析的一个单细胞的整个染色体的补充,减少失败的着床和流产的危险。同时代孕妈妈全部经过IVF妊娠筛查(其他中介机构和试管婴儿医院因为由于没有实验室因而不能完成代孕妈妈筛查,通常是导致代孕妈妈妊娠失败率增高的主要原因。

RGI的执行24 Chromosome分析, 使用芯片的技术, 或阵列比较基因组杂交技术(A - CGH)技术,这种技术比较目前为每一个单细胞的染色体DNA量,比较正常标准。芯片可以执行三种不同类型的样品:极体(从受精卵),卵裂球(3日从胚胎),或囊胚/滋养层(从5天的胚胎)。 在同一个周期内的胚胎转移极体和/或卵裂球测试是可行的,而滋养层测试通常需要在以后的日子和转移胚胎冷冻解冻。RGI的新24 -染色体检测分析的一个单细胞的整个染色体的补充,减少失败的着床和流产的危险,增加拥有一个健康的的宝宝机会。英文全文地址:http://www.reproductivegenetics.com/docs/24_chromosome_microarray_testing.pdf

Yulane's normal IVF ( not surrogate) pregnancy  rate represents ongoing clinical pregnancies that were signed out into ob-care. A comparison of clinical success rates may not be meaningful because patient medical characteristics and treatment approaches may vary from clinic to clinic. The listed pregnancy outcomes reflect ongoing clinical pregnancy rates and not delivered pregnancies. The pregnancy rates are calculated as a percentage of clinical pregnancies achieved per transfers performed, and not as a percentage per cycles started.
 

2008 % Pregnancies
Egg/Oocyte Donor Cycle 65.0%

2008 (non-donor)

% Pregnancies
Fresh Age: <35 41.8%
35-37 38.5%
38-40 35.0%
>= 41 19.0%
 

 

Yulane RGI's Experience for 2003-2005 / IVF Outcome

Yulane RGI's pregnancy rate represents ongoing clinical pregnancies that were signed out into Ob-care. A comparison of clinical success rates may not be meaningful because patient medical characteristics and treatment approaches may vary from clinic to clinic. The listed pregnancy outcomes reflect ongoing clinical pregnancy rates and not delivered pregnancies. The pregnancy rates are calculated as a percentage of clinical pregnancies achieved per transfers performed, and not as a percentage per cycles started.
( * includes affiliated IVF clinics ** patient population differs from non-donor/non-PGD patients see bar graph of outcomes after PGD for Aneuploidy Testing)

2003-2005* # Eggs # Fertilized % Fertilization
Fertilization Rate after ICSI 35,939 28,801 80.1%
Fertilization Rate following TESE and PESA 903 604 66.9%

2003-2005*
# Fert. Eggs # Blastocysts % Blastocysts
Blastocyst Rate 22,485 12,456 55.4%

2003-2005**
# Transfers # Pregnancies % Pregnancies
Day 5 Embryo Transfer (all ages) 2,103 997 47.4%

2003-05 (non-donor/non-PGD)*
# Transfers # Pregnancies % Pregnancies
Fresh Age: <35 1,127 560 49.7%
35-37 471 201 42.7%
38-40 348 102 29.3%
>=41 183 41 22.4%

03-05 (PGD/Aneuploidy)* **
# Transfers # Pregnancies % Pregnancies
Fresh Age: <35 225 103 45.8%
35-37 203 85 41.9%
38-40 272 84 30.9%
>= 41 227 52 22.9%

2003-2005*
# Transfers # Pregnancies % Pregnancies
Frozen/Thawed 584 210 36.0%
Egg/Oocyte Donation 184 106 57.6%